CO₂ and methane are important greenhouse gases, both contributing in increasing amounts towards positive radiative forcing. It is hence important to gain maximum understanding of the carbon cycle in the atmosphere, and the scale of carbon trace gas sources and sinks, not only globally but also on a more regional level. The Orbiting Carbon Observatory (OCO) satellite, scheduled for launch in 2008, is designed for dedicated global mapping of CO₂. In order to investigate the usefulness of a variety of methods, including retrievals from satellite mapping, some preliminary inverse modelling using a Bayesian synthesis technique is performed using pseudodata generated to represent possible future measurement regimes. This study will focus on the ability of in-situ measurements within Australia to reduce the uncertainties in Australian continental CO₂ flux estimates. The specific measurements investigated include a Ghan railway transect between Adelaide (34.9°S, 138.6°E) and Darwin (12.5°S, 130.9°E), and a number of continuous permanent sites. The reduction in flux uncertainties from additional measurements compared to a background inversion is examined, from which it is concluded that measuring on the Ghan railway is potentially worthwhile for reducing uncertainties associated with flux estimates.